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Physician Data Query
Preferred Name | brimonidine tartrate | |
Synonyms |
Alphagan 6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1) |
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Definitions |
The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47419" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47419" NCI Thesaurus) |
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ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000786307 |
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altLabel |
Alphagan 6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1)
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cui |
C0594452 C0077768
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DATE FIRST PUBLISHED |
2017-01-12
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Date last modified |
2017-01-12
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definition |
The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47419" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47419" NCI Thesaurus)
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LT |
TRD
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NCI ID |
C47419
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notation |
CDR0000786307
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ORIG STY |
Drug/agent
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prefLabel |
brimonidine tartrate
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tui |
T109 T121
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