Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

brimonidine tartrate
Synonyms

Alphagan

6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1)

Definitions

The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47419" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47419" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000786307

altLabel

Alphagan

6-Quinoxalinamine, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate(1:1)

cui

C0594452

C0077768

DATE FIRST PUBLISHED

2017-01-12

Date last modified

2017-01-12

definition

The tartrate salt form of brimonidine, an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate also enhances the outflow of aqueous humor. This drug is used in the treatment of glaucoma to reduce intraocular pressure. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47419" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47419" NCI Thesaurus)

LT

TRD

NCI ID

C47419

notation

CDR0000786307

ORIG STY

Drug/agent

prefLabel

brimonidine tartrate

tui

T109

T121

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Mapping To Ontology Source
http://purl.bioontology.org/ontology/MESH/D000068438 MESH CUI
http://purl.bioontology.org/ontology/MESH/D000068438 MESH CUI
http://purl.bioontology.org/ontology/RCD/x03la RCD CUI
http://purl.bioontology.org/ontology/LNC/LA14711-8 LOINC CUI
http://purl.bioontology.org/ontology/RXNORM/153358 RXNORM CUI
http://purl.bioontology.org/ontology/VANDF/4021002 VANDF CUI
http://purl.bioontology.org/ontology/RXNORM/39171 RXNORM CUI
http://purl.bioontology.org/ontology/NDDF/006197 NDDF CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148471 NDFRT CUI
http://purl.bioontology.org/ontology/SCTSPA/386924004 SCTSPA CUI
http://purl.bioontology.org/ontology/RCD/k8j.. RCD CUI
http://purl.bioontology.org/ontology/SNOMEDCT/386924004 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006121 NDFRT CUI
http://purl.bioontology.org/ontology/MSHFRE/D000068438 MSHFRE CUI
http://purl.obolibrary.org/obo/CHEBI_51157 CHEBI LOOM
http://purl.bioontology.org/ontology/MESH/D000068438 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4021002 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/39171 RXNORM LOOM
http://purl.jp/bio/4/id/201606012224582277 IOBC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47419 NCIT LOOM
http://purl.bioontology.org/ontology/NDDF/006197 NDDF LOOM
http://stirdf.jst.go.jp/id/200907052018108593 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15007 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C47419 BERO LOOM
http://purl.obolibrary.org/obo/OMIT_0001283 OMIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148471 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#BrimonidineTartrate GALEN LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017929 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/CHEBI_51157 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_51157 BIOMODELS LOOM
http://purl.bioontology.org/ontology/RCD/k8j.. RCD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386924004 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/MESH_D000068438 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0077768 OCHV LOOM