Physician Data Query

Last uploaded: August 27, 2019
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Preferred Name

ropinirole hydrochloride
Synonyms

SK&F 101468-A

Requip

4-(2-(dipropylamino)ethyl)-2-indolinone monohydrochloride

2(H)-indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, monohydrochloride
Definitions

The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47710" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47710" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000779013
altLabel

SK&F 101468-A

Requip

4-(2-(dipropylamino)ethyl)-2-indolinone monohydrochloride

2(H)-indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, monohydrochloride
CAS Registry

91374-20-8
cui

C0771840

C0593342

C2949746
DATE FIRST PUBLISHED

2016-02-24
Date last modified

2016-02-24
definition

The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47710" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47710" NCI Thesaurus)
LT

TRD
NCI ID

C47710
notation

CDR0000779013
ORIG STY

Drug/agent
prefLabel

ropinirole hydrochloride
tui

T109

T121
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