Physician Data Query

Last uploaded: August 28, 2024
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Preferred Name

pentamidine isethionate
Synonyms

Pentacarinat

Pentam

NebuPent
Definitions

A synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent that appears to interact with the minor groove of AT-rich DNA regions of the pathogen genome, interfering with DNA replication and function. It is effective in the treatment of trypanosomiasis, leishmaniasis, some fungal infections, and Pneumocystis carinii pneumonia in HIV-infected patients. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29349" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29349" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000778947
altLabel

Pentacarinat

Pentam

NebuPent
CAS Registry

140-64-7
cui

C1518952

C0722005

C0030864

C0591959
DATE FIRST PUBLISHED

2016-02-18
Date last modified

2016-02-18
definition

A synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent that appears to interact with the minor groove of AT-rich DNA regions of the pathogen genome, interfering with DNA replication and function. It is effective in the treatment of trypanosomiasis, leishmaniasis, some fungal infections, and Pneumocystis carinii pneumonia in HIV-infected patients. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29349" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29349" NCI Thesaurus)
LT

TRD
NCI ID

C29349
notation

CDR0000778947
NSC Code

620107
ORIG STY

Drug/agent
prefLabel

pentamidine isethionate
tui

T109

T121
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Mapping To Ontology Source
http://purl.bioontology.org/ontology/RXNORM/495527 RXNORM CUI
http://purl.bioontology.org/ontology/MESH/D010419 MESH CUI
http://purl.bioontology.org/ontology/SCTSPA/16826009 SCTSPA CUI
http://purl.bioontology.org/ontology/RCD/x02n5 RCD CUI
http://purl.bioontology.org/ontology/MESH/D010419 MESH CUI
http://purl.bioontology.org/ontology/RXNORM/218646 RXNORM CUI
http://purl.bioontology.org/ontology/SNMI/C-52051 SNMI CUI
http://purl.bioontology.org/ontology/SNOMEDCT/16826009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147312 NDFRT CUI
http://purl.bioontology.org/ontology/MSHFRE/D010419 MSHFRE CUI
http://purl.bioontology.org/ontology/NDDF/002971 NDDF CUI
http://purl.bioontology.org/ontology/NDFRT/N0000178948 NDFRT CUI
http://purl.bioontology.org/ontology/MESH/D010419 MESH CUI
http://purl.bioontology.org/ontology/ATC/P01CX01 ATC CUI
http://purl.bioontology.org/ontology/RXNORM/7995 RXNORM CUI
http://purl.bioontology.org/ontology/VANDF/4019043 VANDF CUI
http://purl.bioontology.org/ontology/MESH/D010419 MESH CUI
http://purl.bioontology.org/ontology/SNMI/C-52051 SNMI LOOM
http://www.co-ode.org/ontologies/galen#PentamidineIsethionate GALEN LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/16826009 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29349 NCIT LOOM
http://purl.obolibrary.org/obo/CHEBI_7977 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_7977 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_7977 BERO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026676 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147312 NDFRT LOOM
http://purl.jp/bio/4/id/200906081455658469 IOBC LOOM
http://stirdf.jst.go.jp/id/200907026630346575 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/002971 NDDF LOOM
http://purl.obolibrary.org/obo/NCIT_C29349 BERO LOOM
http://purl.bioontology.org/ontology/ATC/P01CX01 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/7995 RXNORM LOOM
http://purl.bioontology.org/ontology/VANDF/4019043 VANDF LOOM