Physician Data Query

Last uploaded: August 28, 2024
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Preferred Name

tolazamide
Synonyms

4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide

Norglycin

Tolinase

1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea

U-17835
Definitions

An intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted into five major metabolites that are excreted into the urine. Tolazamide is more potent than tolbutamide and similar in potency to chlorpropamide on a milligram basis. This agent may cause cholestatic jaundice. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29502" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29502" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000775372
altLabel

4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide

Norglycin

Tolinase

1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea

U-17835
cui

C3282883

C0723773

C0040372

C3282882
DATE FIRST PUBLISHED

2015-09-04
Date last modified

2015-09-04
definition

An intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted into five major metabolites that are excreted into the urine. Tolazamide is more potent than tolbutamide and similar in potency to chlorpropamide on a milligram basis. This agent may cause cholestatic jaundice. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29502" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29502" NCI Thesaurus)
LT

TRD
NCI ID

C29502
notation

CDR0000775372
NSC Code

70762
ORIG STY

Drug/agent
prefLabel

tolazamide
tui

T109

T121
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Mapping To Ontology Source
http://purl.bioontology.org/ontology/MESH/D014042 MESH CUI
http://purl.bioontology.org/ontology/RXNORM/10633 RXNORM CUI
http://purl.bioontology.org/ontology/MSHFRE/D014042 MSHFRE CUI
http://purl.bioontology.org/ontology/LNC/MTHU062987 LOINC CUI
http://purl.bioontology.org/ontology/RCD/f39.. RCD CUI
http://purl.bioontology.org/ontology/SCTSPA/387186009 SCTSPA CUI
http://purl.bioontology.org/ontology/LNC/LP17254-1 LOINC CUI
http://purl.bioontology.org/ontology/NDFRT/N0000005916 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146187 NDFRT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387186009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SCTSPA/34393009 SCTSPA CUI
http://purl.bioontology.org/ontology/ATC/A10BB05 ATC CUI
http://purl.bioontology.org/ontology/NDDF/000911 NDDF CUI
http://purl.bioontology.org/ontology/SNOMEDCT/34393009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNMI/C-A2450 SNMI CUI
http://purl.bioontology.org/ontology/MESH/D014042 MESH CUI
http://purl.bioontology.org/ontology/VANDF/4017829 VANDF CUI
http://purl.obolibrary.org/obo/CHEBI_9613 CHEBI LOOM
http://stirdf.jst.go.jp/id/200907064825102033 IOBC LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#tolazamide SDO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29502 NCIT LOOM
http://purl.obolibrary.org/obo/dinto_DB00839 DINTO LOOM
http://purl.obolibrary.org/obo/NCIT_C29502 BERO LOOM
http://purl.jp/bio/4/id/200906070626245573 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.795.834 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00839 MDM LOOM
http://purl.bioontology.org/ontology/RXNORM/10633 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU062987 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.948.828.834 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/f39.. RCD LOOM
http://purl.bioontology.org/ontology/LNC/LP17254-1 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146187 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#Tolazamide GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014042 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00839 FTC LOOM
http://purl.obolibrary.org/obo/MESH_D014042 BERO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387186009 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/OMIT_0014884 OMIT LOOM
http://purl.bioontology.org/ontology/ATC/A10BB05 ATC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017440 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDDF/000911 NDDF LOOM
http://purl.bioontology.org/ontology/SNMI/C-A2450 SNMI LOOM
http://purl.bioontology.org/ontology/MESH/D014042 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4017829 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_9613 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9613 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_9613 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_9613 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_9613 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_9613 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_9613 CHEBI LOOM