loading...| Preferred Name |
miglitol |
|
| Synonyms |
Glyset |
|
| Definitions |
A desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. Compared to acarbose, miglitol is systemically absorbed. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61847" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61847" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000775336 |
|
| altLabel |
Glyset |
|
| CAS Registry |
72432-03-2 |
|
| cui |
C0720692 C0066535 |
|
| DATE FIRST PUBLISHED |
2015-09-03 |
|
| Date last modified |
2015-09-03 |
|
| definition |
A desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. Compared to acarbose, miglitol is systemically absorbed. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61847" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61847" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C61847 |
|
| notation |
CDR0000775336 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
miglitol |
|
| tui |
T109 T121 |