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Physician Data Query
| Preferred Name | rocuronium bromide | |
| Synonyms |
ORG 9426 pyrrolidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)-, bromide Zemuron |
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| Definitions |
The bromide salt form of rocuronium, an intermediate-acting quaternary aminosteroid with muscle relaxant property. Rocuronium bromide competitively binds to the nicotinic receptor at the motor end plate, and antagonizes acetylcholine binding, which results in skeletal muscle relaxation and paralysis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47709" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47709" NCI Thesaurus) |
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| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000767623 |
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| altLabel |
ORG 9426 pyrrolidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)-, bromide Zemuron
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| CAS Registry |
119302-91-9
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| cui |
C0069632 C0950760 C0591463
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| DATE FIRST PUBLISHED |
2014-12-29
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| Date last modified |
2014-12-29
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|
| definition |
The bromide salt form of rocuronium, an intermediate-acting quaternary aminosteroid with muscle relaxant property. Rocuronium bromide competitively binds to the nicotinic receptor at the motor end plate, and antagonizes acetylcholine binding, which results in skeletal muscle relaxation and paralysis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47709" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47709" NCI Thesaurus)
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| LT |
TRD
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| NCI ID |
C47709
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|
| notation |
CDR0000767623
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| ORIG STY |
Drug/agent
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| prefLabel |
rocuronium bromide
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| tui |
T109 T121
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