loading...| Preferred Name |
deferiprone |
|
| Synonyms |
CP20 4(1H)-pyridinone, 3-hydroxy-1,2-dimethyl- DN-180-01-AF Ferriprox APO-066 |
|
| Definitions |
An orally bioavailable bidentate ligand with iron chelating activity. Deferiprone binds to iron in a 3:1 (ligand:iron) molar ratio. By binding to iron, deferiprone is able to remove excess iron from the body. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C73030" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C73030" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000761978 |
|
| altLabel |
CP20 4(1H)-pyridinone, 3-hydroxy-1,2-dimethyl- DN-180-01-AF Ferriprox APO-066 |
|
| CAS Registry |
30652-11-0 |
|
| cui |
C1529907 C0164273 C3887568 C0043832 C3887567 |
|
| DATE FIRST PUBLISHED |
2014-06-11 |
|
| Date last modified |
2014-06-11 |
|
| definition |
An orally bioavailable bidentate ligand with iron chelating activity. Deferiprone binds to iron in a 3:1 (ligand:iron) molar ratio. By binding to iron, deferiprone is able to remove excess iron from the body. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C73030" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C73030" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C73030 |
|
| notation |
CDR0000761978 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
deferiprone |
|
| tui |
T109 T121 |