Physician Data Query

Last uploaded: August 27, 2019
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Preferred Name

edoxaban tosylate
Synonyms

DU-176b

N-(5-chloropyridin-2-yl)-N'-((1S,2R,4S)-4-(N,N- dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro(1,3)thiazolo(5,4-c)pyridine-2- carboxamido)cyclohexyl)oxamide, 4- methylbenzenesulfonate
Definitions

The tosylate salt form of edoxaban, an orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C96542" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C96542" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000758684
altLabel

DU-176b

N-(5-chloropyridin-2-yl)-N'-((1S,2R,4S)-4-(N,N- dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro(1,3)thiazolo(5,4-c)pyridine-2- carboxamido)cyclohexyl)oxamide, 4- methylbenzenesulfonate
cui

C3272851

C2607549
DATE FIRST PUBLISHED

2014-03-06
Date last modified

2014-03-06
definition

The tosylate salt form of edoxaban, an orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C96542" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C96542" NCI Thesaurus)
NCI ID

C96542
notation

CDR0000758684
ORIG STY

Drug/agent
prefLabel

edoxaban tosylate
tui

T109

T121
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