loading...| Preferred Name |
telaprevir |
|
| Synonyms |
VX-950 |
|
| Definitions |
An orally available peptidomimetic small molecule with activity against hepatitis C virus (HCV). Telaprivir is a selective protease inhibitor that targets the viral HCV NS3-4A serine protease and disrupts processing of viral proteins and formation of a viral replication complex. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C81603" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C81603" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000748913 |
|
| altLabel |
VX-950 VRT-111950 MP-424 LY-570310 Incivek |
|
| CAS Registry |
402957-28-2 |
|
| cui |
C1956374 C3154701 C3281323 C3281325 C3281324 C1876229 |
|
| DATE FIRST PUBLISHED |
2013-04-26 |
|
| Date last modified |
2013-04-26 |
|
| definition |
An orally available peptidomimetic small molecule with activity against hepatitis C virus (HCV). Telaprivir is a selective protease inhibitor that targets the viral HCV NS3-4A serine protease and disrupts processing of viral proteins and formation of a viral replication complex. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C81603" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C81603" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C81603 |
|
| notation |
CDR0000748913 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
telaprevir |
|
| tui |
T116 T121 |