Physician Data Query

Last uploaded: August 28, 2024
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Preferred Name

desvenlafaxine succinate
Synonyms

butanedioic acid compound with 4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol (1:1), monohydrate

Pristiq
Definitions

The succinate salt form of desvenlafaxine, a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61704" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61704" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000747472
altLabel

butanedioic acid compound with 4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol (1:1), monohydrate

Pristiq
CAS Registry

386750-22-7
cui

C1742884

C1871864
DATE FIRST PUBLISHED

2013-03-08
Date last modified

2013-03-08
definition

The succinate salt form of desvenlafaxine, a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61704" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61704" NCI Thesaurus)
LT

TRD
NCI ID

C61704
notation

CDR0000747472
ORIG STY

Drug/agent
prefLabel

desvenlafaxine succinate
tui

T109

T121
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