loading...| Preferred Name | oxymorphone hydrochloride | |
| Synonyms |
4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride Opana Numorphan |
|
| Definitions |
The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47648" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47648" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000686446 |
|
| altLabel |
4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride Opana Numorphan |
|
| CAS Registry |
357-07-3 |
|
| cui |
C1723005 C0282275 C0733819 |
|
| DATE FIRST PUBLISHED |
2010-09-28 |
|
| Date last modified |
2010-09-28 |
|
| definition |
The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47648" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47648" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C47648 |
|
| notation |
CDR0000686446 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
oxymorphone hydrochloride |
|
| tui |
T109 T121 |