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Physician Data Query
| Preferred Name | triamcinolone acetonide | |
| Synonyms |
AllerNaze 9-alpha-fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione Nasacort Kenalog Aristocort A |
|
| Definitions |
The acetonide salt of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activities. Triamcinolone binds to specific cytosolic glucocorticoid receptors, which subsequently interact with the glucocorticoid receptor response element on DNA, gene expression is altered so that the synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. Consequently, chronic inflammatory and autoimmune reactions are reduced. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C48027" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48027" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000649799 |
|
| altLabel |
AllerNaze 9-alpha-fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione Nasacort Kenalog Aristocort A
|
|
| CAS Registry |
76-25-5
|
|
| cui |
C2608734 C0699689 C0040866 C0718648 C0594040
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|
| DATE FIRST PUBLISHED |
2009-07-14
|
|
| Date last modified |
2009-07-14
|
|
| definition |
The acetonide salt of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activities. Triamcinolone binds to specific cytosolic glucocorticoid receptors, which subsequently interact with the glucocorticoid receptor response element on DNA, gene expression is altered so that the synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. Consequently, chronic inflammatory and autoimmune reactions are reduced. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C48027" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48027" NCI Thesaurus)
|
|
| LT |
TRD
|
|
| NCI ID |
C48027
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|
| notation |
CDR0000649799
|
|
| NSC Code |
21916
|
|
| ORIG STY |
Drug/agent
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|
| prefLabel |
triamcinolone acetonide
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|
| tui |
T109 T121
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