Preferred Name |
paraganglioma |
|
Synonyms |
Neoplasm of the Paraganglion Tumor of Paraganglion |
|
Definitions |
A benign or malignant neoplasm arising from paraganglia located along the sympathetic or parasympathetic nerves. Infrequently, it may arise outside the usual distribution of the sympathetic and parasympathetic paraganglia. Tumors arising from the adrenal gland medulla are called pheochromocytomas. Morphologically, paragangliomas usually display a nesting (Zellballen) growth pattern. There are no reliable morphologic criteria to distinguish between benign and malignant paragangliomas. The only definitive indicator of malignancy is the presence of regional or distant metastases. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C3308" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C3308" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000639696 |
|
altLabel |
Neoplasm of the Paraganglion Tumor of the Paraganglion Paraganglion Neoplasm Paraganglionic Neoplasm Paraganglionic Tumor Paraganglion Tumor Neoplasm of Paraganglion Tumor of Paraganglion |
|
Associated genetic condition |
http://purl.bioontology.org/ontology/PDQ/CDR0000042846 http://purl.bioontology.org/ontology/PDQ/CDR0000042845 |
|
cui |
C0030421 |
|
DATE FIRST PUBLISHED |
2009-03-31 |
|
Date last modified |
2017-03-30 |
|
definition |
A benign or malignant neoplasm arising from paraganglia located along the sympathetic or parasympathetic nerves. Infrequently, it may arise outside the usual distribution of the sympathetic and parasympathetic paraganglia. Tumors arising from the adrenal gland medulla are called pheochromocytomas. Morphologically, paragangliomas usually display a nesting (Zellballen) growth pattern. There are no reliable morphologic criteria to distinguish between benign and malignant paragangliomas. The only definitive indicator of malignancy is the presence of regional or distant metastases. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C3308" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C3308" NCI Thesaurus) |
|
NCI ID |
C3308 |
|
notation |
CDR0000639696 |
|
ORIG STY |
Neoplasm diagnosis |
|
prefLabel |
paraganglioma |
|
tui |
T191 |
|
subClassOf |