loading...| Preferred Name |
etodolac |
|
| Synonyms |
Lodine |
|
| Definitions |
A pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic activities. Etodolac inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. It also inhibits platelet aggregation by blocking platelet cyclooxygenase and the subsequent formation of thromboxane A2. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47526" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47526" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000561499 |
|
| altLabel |
Lodine 1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic Acid Etodolic Acid Ultradol |
|
| CAS Registry |
41340-25-4 |
|
| cui |
C0059865 C0700001 C0700766 |
|
| DATE FIRST PUBLISHED |
2007-08-03 |
|
| definition |
A pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic activities. Etodolac inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. It also inhibits platelet aggregation by blocking platelet cyclooxygenase and the subsequent formation of thromboxane A2. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47526" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47526" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C47526 |
|
| notation |
CDR0000561499 |
|
| NSC Code |
282126 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
etodolac |
|
| tui |
T109 T121 |