Preferred Name |
sufentanil citrate |
|
Synonyms |
N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide Citrate |
|
Definitions |
The citrate salt form of sufentanil, a synthetic congener of fentanyl and related to the phenylpieridines, with analgesic property. Sufentanil citrate binds to and activates the mu-opioid receptor, thereby producing analgesia, respiratory depression, miosis, reduced gastrointestinal motility, and euphoria. In addition, this agent has a more rapid onset of action and shorter duration of action compared to fentanyl. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47731" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47731" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000524060 |
|
altLabel |
N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide Citrate N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)-N-phenylpropionamide Citrate Fentatienil Propanamide, N-(4-(methoxymethyl)-1-(2-(thienyl)ethyl)-4-piperidinyl)-N-phenyl-, 2-hydroxy-1,2,3-propanetricarboxylate(1:1) Sufenta |
|
CAS Registry |
60561-17-3 |
|
cui |
C0162792 C0733851 |
|
DATE FIRST PUBLISHED |
2006-12-01 |
|
definition |
The citrate salt form of sufentanil, a synthetic congener of fentanyl and related to the phenylpieridines, with analgesic property. Sufentanil citrate binds to and activates the mu-opioid receptor, thereby producing analgesia, respiratory depression, miosis, reduced gastrointestinal motility, and euphoria. In addition, this agent has a more rapid onset of action and shorter duration of action compared to fentanyl. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47731" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47731" NCI Thesaurus) |
|
LT |
TRD |
|
NCI ID |
C47731 |
|
notation |
CDR0000524060 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
sufentanil citrate |
|
tui |
T109 T121 |