loading...| Preferred Name |
oxycodone hydrochloride |
|
| Synonyms |
Oxecta |
|
| Definitions |
The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C48010" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48010" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000508980 |
|
| altLabel |
Oxecta OxyContin OxyNorm Roxicodone 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride |
|
| CAS Registry |
124-90-3 |
|
| cui |
C3160522 C0722364 C0282274 C0723149 C1602113 |
|
| DATE FIRST PUBLISHED |
2006-09-15 |
|
| Date last modified |
2016-02-02 |
|
| definition |
The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C48010" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48010" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C48010 |
|
| notation |
CDR0000508980 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
oxycodone hydrochloride |
|
| tui |
T109 T121 |