Physician Data Query

Last uploaded: August 27, 2019
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Preferred Name

escitalopram oxalate
Synonyms

5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-,(1S)-, ethanedioate(1:1)

Lexapro

Lu 26-054-0
Definitions

The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (CNS), thereby potentiating CNS serotonergic activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47518" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47518" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000497135
altLabel

5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-,(1S)-, ethanedioate(1:1)

Lexapro

Lu 26-054-0
CAS Registry

219861-08-2
cui

C1765323

C1170746

C1170371
DATE FIRST PUBLISHED

2006-07-25
definition

The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), escitalopram blocks the reuptake of serotonin by neurons in the central nervous system (CNS), thereby potentiating CNS serotonergic activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47518" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47518" NCI Thesaurus)
LT

TRD
NCI ID

C47518
notation

CDR0000497135
ORIG STY

Drug/agent
prefLabel

escitalopram oxalate
tui

T109

T121
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