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Physician Data Query
| Preferred Name | iloprost | |
| Synonyms |
Ciloprost ZK 36374 (E)-(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-delta(sup 2(1H),delta)-pentalenevaleric Acid Ventavis iloprost clathrate pentanoic acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene) |
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| Definitions |
A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing vasodilation, inhibition of platelet aggregation, and decreased tumor cell adhesion to endothelium among other effects. Prostacyclin is a naturally occurring eicosanoid with anti-inflammatory, antineoplastic, and anti-metastatic properties. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C48397" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48397" NCI Thesaurus) |
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| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000365679 |
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| altLabel |
Ciloprost ZK 36374 (E)-(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-delta(sup 2(1H),delta)-pentalenevaleric Acid Ventavis iloprost clathrate pentanoic acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)
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| cui |
C1541936 C1704333 C0079594 C0733549
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| DATE FIRST PUBLISHED |
2004-04-23
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| Date last modified |
2006-05-09
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|
| definition |
A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing vasodilation, inhibition of platelet aggregation, and decreased tumor cell adhesion to endothelium among other effects. Prostacyclin is a naturally occurring eicosanoid with anti-inflammatory, antineoplastic, and anti-metastatic properties. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C48397" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48397" NCI Thesaurus)
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| LT |
TRD
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| NCI ID |
C48397
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| notation |
CDR0000365679
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| ORIG STY |
Drug/agent
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| prefLabel |
iloprost
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| tui |
T109 T121
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