Preferred Name | moxifloxacin hydrochloride | |
Synonyms |
Viagmox Avelox BAY 128039 MOXI |
|
Definitions |
The hydrochloride salt of a fluoroquinolone antibacterial antibiotic. Moxifloxacin binds to and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, resulting in inhibition of DNA replication and repair and cell death in sensitive bacterial species. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C38696" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38696" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000306456 |
|
altLabel |
Viagmox Avelox BAY 128039 MOXI |
|
cui |
C0875968 C0878537 C0754517 C1513705 C0536495 |
|
DATE FIRST PUBLISHED |
2003-05-23 |
|
Date last modified |
2006-05-08 |
|
definition |
The hydrochloride salt of a fluoroquinolone antibacterial antibiotic. Moxifloxacin binds to and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, resulting in inhibition of DNA replication and repair and cell death in sensitive bacterial species. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C38696" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38696" NCI Thesaurus) |
|
LT |
TRD |
|
NCI ID |
C38696 |
|
notation |
CDR0000306456 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
moxifloxacin hydrochloride |
|
tui |
T109 T195 T121 |