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Physician Data Query
Preferred Name | buspirone hydrochloride | |
Synonyms |
Buspar |
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Definitions |
The hydrochloride salt of an anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C26641" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26641" NCI Thesaurus) |
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ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000270391 |
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altLabel |
Buspar
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cui |
C0700444 C0600122
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DATE FIRST PUBLISHED |
2003-01-26
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Date last modified |
2006-07-27
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definition |
The hydrochloride salt of an anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C26641" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26641" NCI Thesaurus)
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LT |
TRD
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NCI ID |
C26641
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notation |
CDR0000270391
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ORIG STY |
Drug/agent
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prefLabel |
buspirone hydrochloride
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tui |
T109 T121
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