Preferred Name |
modafinil |
|
Synonyms |
Provigil |
|
Definitions |
A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C26661" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26661" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000256449 |
|
altLabel |
Provigil |
|
cui |
C0066677 C0722882 |
|
Date last modified |
2006-05-10 |
|
definition |
A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C26661" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26661" NCI Thesaurus) |
|
Legacy PDQ ID |
11399 |
|
LT |
TRD |
|
NCI ID |
C26661 |
|
notation |
CDR0000256449 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
modafinil |
|
tui |
T109 T121 |