Preferred Name | liothyronine sodium | |
Synonyms |
Triostat Cytomel |
|
Definitions |
The sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2581" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2581" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000043629 |
|
altLabel |
Triostat Cytomel |
|
cui |
C0723907 C0010826 C0546882 |
|
Date last modified |
2006-12-15 |
|
definition |
The sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2581" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2581" NCI Thesaurus) |
|
Legacy PDQ ID |
8914 |
|
LT |
TRD |
|
NCI ID |
C2581 |
|
notation |
CDR0000043629 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
liothyronine sodium |
|
tui |
T125 T109 T116 T121 |