loading...| Preferred Name |
tropisetron |
|
| Synonyms |
ICS 205-930 |
|
| Definitions |
An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy-and radiotherapy-induced nausea and vomiting. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1131" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1131" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000043507 |
|
| altLabel |
ICS 205-930 Navoban |
|
| CAS Registry |
89565-68-4 |
|
| cui |
C0244753 C0701391 C0063322 |
|
| Date last modified |
2006-08-02 |
|
| definition |
An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy-and radiotherapy-induced nausea and vomiting. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1131" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1131" NCI Thesaurus) |
|
| Legacy PDQ ID |
8744 |
|
| LT |
TRD |
|
| NCI ID |
C1131 |
|
| notation |
CDR0000043507 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
tropisetron |
|
| tui |
T109 T121 |