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Physician Data Query
Last uploaded:
August 28, 2024
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| Preferred Name | voriconazole | |
| Synonyms |
Vfend VCZ |
|
| Definitions |
A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1707" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1707" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042690 |
|
| altLabel |
Vfend VCZ
|
|
| Component of | ||
| cui |
C0393080 C1136812
|
|
| Date last modified |
2008-10-22
|
|
| definition |
A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1707" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1707" NCI Thesaurus)
|
|
| Legacy PDQ ID |
6476
|
|
| LT |
TRD
|
|
| NCI ID |
C1707
|
|
| notation |
CDR0000042690
|
|
| ORIG STY |
Drug/agent
|
|
| prefLabel |
voriconazole
|
|
| tui |
T109 T121
|
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