Preferred Name |
voriconazole |
|
Synonyms |
Vfend VCZ |
|
Definitions |
A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1707" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1707" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042690 |
|
altLabel |
Vfend VCZ |
|
Component of | ||
cui |
C0393080 C1136812 |
|
Date last modified |
2008-10-22 |
|
definition |
A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1707" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1707" NCI Thesaurus) |
|
Legacy PDQ ID |
6476 |
|
LT |
TRD |
|
NCI ID |
C1707 |
|
notation |
CDR0000042690 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
voriconazole |
|
tui |
T109 T121 |