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Physician Data Query
Last uploaded:
August 28, 2024
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| Preferred Name | dextromethorphan hydrobromide | |
| Synonyms |
DXM |
|
| Definitions |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C423" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C423" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042490 |
|
| altLabel |
DXM
|
|
| Component of | ||
| cui |
C0350422
|
|
| Date last modified |
2010-06-01
|
|
| definition |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C423" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C423" NCI Thesaurus)
|
|
| Legacy PDQ ID |
6022
|
|
| NCI ID |
C423
|
|
| notation |
CDR0000042490
|
|
| ORIG STY |
Drug/agent
|
|
| prefLabel |
dextromethorphan hydrobromide
|
|
| tui |
T109 T121
|
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