| Synonyms |
deltadehydrocortisone
Ofisolona
Predniment
PRD
Panasol-S
17,21-dihydroxypregna-1,4-diene-3,11,20-trione
Paracort
1;2-dehydrocortisone
Deltison
Prednisonum
Deltacortene
Prednitone
Predicorten
Decortisyl
PRED
Deltra
Cortancyl
Dacortin
deltacortisone
delta 1-cortisone
Decorton
Prednidib
Meprosona-F
metacortandracin
Econosone
Promifen
Panafcort
DeCortin
Predicor
Prednilonga
Adasone
1, 2-dehydrocortisone
Delta(1)-Cortisone
Prednicort
Predeltin
Servisone
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| Definitions |
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C770" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C770" NCI Thesaurus)
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| altLabel |
deltadehydrocortisone Ofisolona Predniment PRD Panasol-S 17,21-dihydroxypregna-1,4-diene-3,11,20-trione Paracort 1;2-dehydrocortisone Deltison Prednisonum Deltacortene Prednitone Predicorten Decortisyl PRED Deltra Cortancyl Dacortin deltacortisone delta 1-cortisone Decorton Prednidib Meprosona-F metacortandracin Econosone Promifen Panafcort DeCortin Predicor Prednilonga Adasone 1, 2-dehydrocortisone Delta(1)-Cortisone Prednicort Predeltin Servisone
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| definition |
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C770" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C770" NCI Thesaurus)
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