loading...| Preferred Name | verteporfin | |
| Synonyms |
Benzoporphyrin Derivative Monoacid Ring A BPD-MA Visudyne |
|
| Definitions |
A synthetic light-activated agent with photodynamic activity. Upon systemic administration, verteporfin accumulates in neovessels in the eye and, once stimulated by nonthermal red light in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to neovascular endothelium and blood vessel occlusion. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1014" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1014" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042130 |
|
| altLabel |
Benzoporphyrin Derivative Monoacid Ring A BPD-MA Visudyne |
|
| CAS Registry |
129497-78-5 |
|
| cui |
C0387288 C0876212 |
|
| Date last modified |
2006-08-02 |
|
| definition |
A synthetic light-activated agent with photodynamic activity. Upon systemic administration, verteporfin accumulates in neovessels in the eye and, once stimulated by nonthermal red light in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to neovascular endothelium and blood vessel occlusion. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1014" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1014" NCI Thesaurus) |
|
| Legacy PDQ ID |
5366 |
|
| LT |
TRD |
|
| NCI ID |
C1014 |
|
| notation |
CDR0000042130 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
verteporfin |
|
| tui |
T109 T121 |