loading...| Preferred Name |
perflubron |
|
| Synonyms |
Imagent |
|
| Definitions |
A synthetic radiopaque liquid form of perfluorooctyl bromide. Used as a contrast agent for magnetic resonance imaging (MRI), perflubron is also used as a liquid ventilation agent to improve pulmonary gas exchange and lung compliance and may be used in surgery to reduce or eliminate the need for a donor blood. Ventilation with perfluorocarbon fluid improves lung function in conditions involving surfactant deficiency and dysfunction, including respiratory distress syndrome and adult respiratory distress syndrome. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1422" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1422" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000041963 |
|
| altLabel |
Imagent perfluorooctylbromide PFOB |
|
| CAS Registry |
423-55-2 |
|
| Component of | ||
| cui |
C0993621 C0162922 |
|
| definition |
A synthetic radiopaque liquid form of perfluorooctyl bromide. Used as a contrast agent for magnetic resonance imaging (MRI), perflubron is also used as a liquid ventilation agent to improve pulmonary gas exchange and lung compliance and may be used in surgery to reduce or eliminate the need for a donor blood. Ventilation with perfluorocarbon fluid improves lung function in conditions involving surfactant deficiency and dysfunction, including respiratory distress syndrome and adult respiratory distress syndrome. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1422" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1422" NCI Thesaurus) |
|
| Legacy PDQ ID |
5187 |
|
| LT |
TRD |
|
| NCI ID |
C1422 |
|
| notation |
CDR0000041963 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
perflubron |
|
| tui |
T109 T130 |