Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

thymopentin
Synonyms

Timunox

N-(N-(N-(N(2)-L-Arginyl-L-Lysyl)-L-alpha-Aspartyl)-L-Valyl)-L-tyrosine

Mepentil

Immunox

Sintomodulina

Definitions

A synthetic pentapeptide which is the active site of the naturally occurring hormone thymopoietin with immunomodulating properties. Thymopentin enhances the production of thymic T cells and may help restore immunocompetence in immunosuppressed subjects. This agent also augments the effects of ionizing radiation by arresting cancer cells in the G2/M phase of the cell cycle. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1294" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1294" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000041655

altLabel

Timunox

N-(N-(N-(N(2)-L-Arginyl-L-Lysyl)-L-alpha-Aspartyl)-L-Valyl)-L-tyrosine

Mepentil

Immunox

Sintomodulina

CAS Registry

69558-55-0

cui

C0918006

C1515435

C1515436

C0080225

C1831597

definition

A synthetic pentapeptide which is the active site of the naturally occurring hormone thymopoietin with immunomodulating properties. Thymopentin enhances the production of thymic T cells and may help restore immunocompetence in immunosuppressed subjects. This agent also augments the effects of ionizing radiation by arresting cancer cells in the G2/M phase of the cell cycle. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1294" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1294" NCI Thesaurus)

IND Code

39678

Legacy PDQ ID

4817

LT

TRD

NCI ID

C1294

notation

CDR0000041655

NSC Code

645363

ORIG STY

Drug/agent

prefLabel

thymopentin

tui

T116

T123

T121

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Mapping To Ontology Source
http://purl.bioontology.org/ontology/MESH/D016305 MESH CUI
http://purl.bioontology.org/ontology/RXNORM/40230 RXNORM CUI
http://purl.bioontology.org/ontology/ATC/L03AX09 ATC CUI
http://purl.bioontology.org/ontology/MSHFRE/D016305 MSHFRE CUI
http://purl.bioontology.org/ontology/MESH/D016305 MESH CUI
http://purl.bioontology.org/ontology/NDFRT/N0000167482 NDFRT CUI
http://purl.bioontology.org/ontology/NDDF/006776 NDDF CUI
http://purl.obolibrary.org/obo/CHEBI_135870 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_135870 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_135870 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_135870 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_135870 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_135870 DDSS LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1294 NCIT LOOM
http://purl.obolibrary.org/obo/NCIT_C1294 BERO LOOM
http://purl.bioontology.org/ontology/RXNORM/40230 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/L03AX09 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0080225 OCHV LOOM
http://purl.obolibrary.org/obo/MESH_D016305 BERO LOOM
http://purl.obolibrary.org/obo/OMIT_0016837 OMIT LOOM
http://purl.bioontology.org/ontology/MESH/D016305 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D016305 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00019061 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D06.472.910.800.850 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15319 OCHV LOOM
https://go.drugbank.com/drugs/DB11996 MDM LOOM
http://purl.jp/bio/4/id/200906037367853244 IOBC LOOM
http://stirdf.jst.go.jp/id/200907067075113622 IOBC LOOM