loading...| Preferred Name |
nilutamide |
|
| Synonyms |
5,5-Dimethyl-3-[4-nitro-3-(trifluoro-methyl)phenyl]-2,4-imidazolidinedione RU-23908 1-(3'-Trifluoromethyl-4'-nitrophenyl)-4,4-dimethylimidazoline-3,5-dione ANAN Nilandron Anandron |
|
| Definitions |
A synthetic, nonsteroidal agent with antiandrogenic properties. Nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by testosterone and other androgens; this agent may inhibit androgen-dependent growth of normal and neoplastic prostate cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1173" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1173" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000040450 |
|
| altLabel |
5,5-Dimethyl-3-[4-nitro-3-(trifluoro-methyl)phenyl]-2,4-imidazolidinedione RU-23908 1-(3'-Trifluoromethyl-4'-nitrophenyl)-4,4-dimethylimidazoline-3,5-dione ANAN Nilandron Anandron |
|
| CAS Registry |
63612-50-0 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000358327 http://purl.bioontology.org/ontology/PDQ/CDR0000042913 http://purl.bioontology.org/ontology/PDQ/CDR0000042915 http://purl.bioontology.org/ontology/PDQ/CDR0000038844 |
|
| cui |
C0740137 C0740136 C0068771 C0722107 |
|
| Date last modified |
2006-09-07 |
|
| definition |
A synthetic, nonsteroidal agent with antiandrogenic properties. Nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by testosterone and other androgens; this agent may inhibit androgen-dependent growth of normal and neoplastic prostate cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1173" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1173" NCI Thesaurus) |
|
| Legacy PDQ ID |
3324 |
|
| LT |
TRD |
|
| NCI ID |
C1173 |
|
| notation |
CDR0000040450 |
|
| NSC Code |
684588 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
nilutamide |
|
| tui |
T109 T121 |