Physician Data Query

Last uploaded: August 28, 2024
Preferred Name

hydrazine sulfate
Synonyms

Sehydrin

Definitions

The synthetic sulfate salt of hydrazine, a derivative of ammonia. Hydrazine inhibits the enzyme phosphoenol pyruvate carboxykinase, thereby blocking gluconeogenesis. This agent has been reported to decrease the excessive energy needs and cachexia of cancer patients. Classified as a likely human carcinogen, hydrazine sulfate is also a weak inhibitor of mono-amine oxidase (MAO). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1129" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1129" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000040141

altLabel

Sehydrin

CAS Registry

10034-93-2

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000040142

http://purl.bioontology.org/ontology/PDQ/CDR0000041187

cui

C1512522

C0063067

Date last modified

2006-12-20

definition

The synthetic sulfate salt of hydrazine, a derivative of ammonia. Hydrazine inhibits the enzyme phosphoenol pyruvate carboxykinase, thereby blocking gluconeogenesis. This agent has been reported to decrease the excessive energy needs and cachexia of cancer patients. Classified as a likely human carcinogen, hydrazine sulfate is also a weak inhibitor of mono-amine oxidase (MAO). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1129" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1129" NCI Thesaurus)

IND Code

33233

Legacy PDQ ID

2906

LT

TRD

NCI ID

C1129

notation

CDR0000040141

ORIG STY

Drug/agent

prefLabel

hydrazine sulfate

tui

T197

T109

T121

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