Physician Data Query

Last uploaded: August 28, 2024
Preferred Name

daunorubicin hydrochloride
Synonyms

L-lyxo-hexopyranoside, 3.beta.-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-metldioxo-1a-naphthacenyl 3-amino-2,3,6-trideoxy-,.alpha.-,hydrochloride

5,12-naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-(9CI)

Ondena

daunoblastine

Daunoblastin

cloridrato de daunorubicina

daunomycin hydrochloride

rubidomycin hydrochloride

Cerubidin

RP-13057

Rubilem

FI-6339

5,12-naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-, (8S-cis)-, hydrochloride

Cerubidine

Daunoblastina

Definitions

The hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1583" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1583" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039779

altLabel

L-lyxo-hexopyranoside, 3.beta.-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-metldioxo-1a-naphthacenyl 3-amino-2,3,6-trideoxy-,.alpha.-,hydrochloride

5,12-naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-(9CI)

Ondena

daunoblastine

Daunoblastin

cloridrato de daunorubicina

daunomycin hydrochloride

rubidomycin hydrochloride

Cerubidin

RP-13057

Rubilem

FI-6339

5,12-naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-, (8S-cis)-, hydrochloride

Cerubidine

Daunoblastina

CAS Registry

23541-50-6

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000039047

http://purl.bioontology.org/ontology/PDQ/CDR0000038978

http://purl.bioontology.org/ontology/PDQ/CDR0000037960

http://purl.bioontology.org/ontology/PDQ/CDR0000041118

http://purl.bioontology.org/ontology/PDQ/CDR0000041080

http://purl.bioontology.org/ontology/PDQ/CDR0000039781

http://purl.bioontology.org/ontology/PDQ/CDR0000041164

http://purl.bioontology.org/ontology/PDQ/CDR0000040156

http://purl.bioontology.org/ontology/PDQ/CDR0000041314

http://purl.bioontology.org/ontology/PDQ/CDR0000350092

http://purl.bioontology.org/ontology/PDQ/CDR0000043039

http://purl.bioontology.org/ontology/PDQ/CDR0000042361

http://purl.bioontology.org/ontology/PDQ/CDR0000041031

http://purl.bioontology.org/ontology/PDQ/CDR0000042282

http://purl.bioontology.org/ontology/PDQ/CDR0000037927

http://purl.bioontology.org/ontology/PDQ/CDR0000042363

http://purl.bioontology.org/ontology/PDQ/CDR0000038662

http://purl.bioontology.org/ontology/PDQ/CDR0000041830

http://purl.bioontology.org/ontology/PDQ/CDR0000042341

http://purl.bioontology.org/ontology/PDQ/CDR0000038875

http://purl.bioontology.org/ontology/PDQ/CDR0000039772

http://purl.bioontology.org/ontology/PDQ/CDR0000331877

http://purl.bioontology.org/ontology/PDQ/CDR0000039095

http://purl.bioontology.org/ontology/PDQ/CDR0000043395

http://purl.bioontology.org/ontology/PDQ/CDR0000041812

http://purl.bioontology.org/ontology/PDQ/CDR0000039637

http://purl.bioontology.org/ontology/PDQ/CDR0000042256

http://purl.bioontology.org/ontology/PDQ/CDR0000038872

http://purl.bioontology.org/ontology/PDQ/CDR0000042416

http://purl.bioontology.org/ontology/PDQ/CDR0000350091

http://purl.bioontology.org/ontology/PDQ/CDR0000041594

http://purl.bioontology.org/ontology/PDQ/CDR0000409579

http://purl.bioontology.org/ontology/PDQ/CDR0000039040

http://purl.bioontology.org/ontology/PDQ/CDR0000042244

http://purl.bioontology.org/ontology/PDQ/CDR0000043269

http://purl.bioontology.org/ontology/PDQ/CDR0000042392

http://purl.bioontology.org/ontology/PDQ/CDR0000039529

http://purl.bioontology.org/ontology/PDQ/CDR0000040892

http://purl.bioontology.org/ontology/PDQ/CDR0000037826

http://purl.bioontology.org/ontology/PDQ/CDR0000306480

http://purl.bioontology.org/ontology/PDQ/CDR0000041082

http://purl.bioontology.org/ontology/PDQ/CDR0000043401

http://purl.bioontology.org/ontology/PDQ/CDR0000039537

http://purl.bioontology.org/ontology/PDQ/CDR0000257882

http://purl.bioontology.org/ontology/PDQ/CDR0000391013

http://purl.bioontology.org/ontology/PDQ/CDR0000041328

http://purl.bioontology.org/ontology/PDQ/CDR0000043394

http://purl.bioontology.org/ontology/PDQ/CDR0000043295

http://purl.bioontology.org/ontology/PDQ/CDR0000037970

http://purl.bioontology.org/ontology/PDQ/CDR0000040975

http://purl.bioontology.org/ontology/PDQ/CDR0000041297

http://purl.bioontology.org/ontology/PDQ/CDR0000040123

http://purl.bioontology.org/ontology/PDQ/CDR0000041733

http://purl.bioontology.org/ontology/PDQ/CDR0000042255

http://purl.bioontology.org/ontology/PDQ/CDR0000038285

http://purl.bioontology.org/ontology/PDQ/CDR0000037787

http://purl.bioontology.org/ontology/PDQ/CDR0000039462

http://purl.bioontology.org/ontology/PDQ/CDR0000361540

http://purl.bioontology.org/ontology/PDQ/CDR0000038287

http://purl.bioontology.org/ontology/PDQ/CDR0000040956

http://purl.bioontology.org/ontology/PDQ/CDR0000038291

http://purl.bioontology.org/ontology/PDQ/CDR0000038200

http://purl.bioontology.org/ontology/PDQ/CDR0000043405

http://purl.bioontology.org/ontology/PDQ/CDR0000039634

http://purl.bioontology.org/ontology/PDQ/CDR0000040412

http://purl.bioontology.org/ontology/PDQ/CDR0000042960

http://purl.bioontology.org/ontology/PDQ/CDR0000043298

http://purl.bioontology.org/ontology/PDQ/CDR0000037925

http://purl.bioontology.org/ontology/PDQ/CDR0000043396

http://purl.bioontology.org/ontology/PDQ/CDR0000043506

http://purl.bioontology.org/ontology/PDQ/CDR0000043125

http://purl.bioontology.org/ontology/PDQ/CDR0000042448

http://purl.bioontology.org/ontology/PDQ/CDR0000043404

http://purl.bioontology.org/ontology/PDQ/CDR0000039043

http://purl.bioontology.org/ontology/PDQ/CDR0000041732

http://purl.bioontology.org/ontology/PDQ/CDR0000037833

http://purl.bioontology.org/ontology/PDQ/CDR0000041598

http://purl.bioontology.org/ontology/PDQ/CDR0000041930

http://purl.bioontology.org/ontology/PDQ/CDR0000041179

http://purl.bioontology.org/ontology/PDQ/CDR0000041717

http://purl.bioontology.org/ontology/PDQ/CDR0000041315

http://purl.bioontology.org/ontology/PDQ/CDR0000042406

http://purl.bioontology.org/ontology/PDQ/CDR0000038397

http://purl.bioontology.org/ontology/PDQ/CDR0000039533

http://purl.bioontology.org/ontology/PDQ/CDR0000041007

http://purl.bioontology.org/ontology/PDQ/CDR0000041734

http://purl.bioontology.org/ontology/PDQ/CDR0000039820

http://purl.bioontology.org/ontology/PDQ/CDR0000041260

http://purl.bioontology.org/ontology/PDQ/CDR0000041035

http://purl.bioontology.org/ontology/PDQ/CDR0000041464

http://purl.bioontology.org/ontology/PDQ/CDR0000038930

http://purl.bioontology.org/ontology/PDQ/CDR0000038556

http://purl.bioontology.org/ontology/PDQ/CDR0000350090

http://purl.bioontology.org/ontology/PDQ/CDR0000037832

http://purl.bioontology.org/ontology/PDQ/CDR0000043505

http://purl.bioontology.org/ontology/PDQ/CDR0000040957

http://purl.bioontology.org/ontology/PDQ/CDR0000038015

http://purl.bioontology.org/ontology/PDQ/CDR0000037835

http://purl.bioontology.org/ontology/PDQ/CDR0000041681

http://purl.bioontology.org/ontology/PDQ/CDR0000040873

http://purl.bioontology.org/ontology/PDQ/CDR0000042470

http://purl.bioontology.org/ontology/PDQ/CDR0000039464

http://purl.bioontology.org/ontology/PDQ/CDR0000441004

http://purl.bioontology.org/ontology/PDQ/CDR0000038309

cui

C1522600

C1511734

C0282123

C1511735

C1522599

C1511736

C0701062

C0594564

C0969848

C0701063

Date last modified

2017-11-03

definition

The hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1583" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1583" NCI Thesaurus)

Legacy PDQ ID

244

LT

TRD

NCI ID

C1583

notation

CDR0000039779

NSC Code

82151

83142

ORIG STY

Drug/agent

prefLabel

daunorubicin hydrochloride

tui

T109

T195

T121

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Create mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/MSHFRE/D003630 MSHFRE CUI
http://purl.bioontology.org/ontology/MESH/D003630 MESH CUI
http://purl.bioontology.org/ontology/RCD/x03m6 RCD CUI
http://purl.bioontology.org/ontology/MESH/C000847 MESH CUI
http://purl.bioontology.org/ontology/SNMI/C-C142C SNMI CUI
http://purl.bioontology.org/ontology/SNOMEDCT/65972004 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDDF/002662 NDDF CUI
http://purl.bioontology.org/ontology/SCTSPA/65972004 SCTSPA CUI
http://purl.bioontology.org/ontology/MESH/D003630 MESH CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146402 NDFRT CUI
http://purl.bioontology.org/ontology/SNMI/C-780B1 SNMI CUI
http://purl.bioontology.org/ontology/VANDF/4018061 VANDF CUI
http://purl.bioontology.org/ontology/RXNORM/81992 RXNORM CUI
http://purl.bioontology.org/ontology/NDFRT/N0000179404 NDFRT CUI
http://purl.bioontology.org/ontology/MESH/D003630 MESH CUI
http://www.co-ode.org/ontologies/galen#DaunorubicinHydrochloride GALEN LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/65972004 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/NCIT_C1583 BERO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1583 NCIT LOOM
http://purl.obolibrary.org/obo/CHEBI_31456 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_31456 CHEBI LOOM
http://id.nlm.nih.gov/mesh/D003630 MDM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146402 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-780B1 SNMI LOOM
http://purl.jp/bio/4/id/200906081518054240 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4018061 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/81992 RXNORM LOOM