loading...| Preferred Name |
clomiphene citrate |
|
| Synonyms |
Clomid |
|
| Definitions |
The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C379" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C379" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039542 |
|
| altLabel |
Clomid Serophene 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]triethylamine citrate (1:1) |
|
| CAS Registry |
50-41-9 |
|
| cui |
C0546859 C0591268 C0036748 |
|
| definition |
The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C379" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C379" NCI Thesaurus) |
|
| Legacy PDQ ID |
219 |
|
| LT |
TRD |
|
| NCI ID |
C379 |
|
| notation |
CDR0000039542 |
|
| NSC Code |
35770 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
clomiphene citrate |
|
| tui |
T109 T121 |