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Physician Data Query
Preferred Name | danazol | |
Synonyms |
Danocrine Bonzol 17alpha-ethynyl-17beta-hydroxy-4-androsteno[2,3-d]isoxazole Win-17757 DAN 1-ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental[7,8]phenanthro[3,2-d]isoxazol-1-ol Winobanin Danol Cyclomen (17alpha)-pregna-2,4-dien-20-yno[2,3-d]-isoxazol-17-ol Chronogyn Ladogal Danoval |
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Definitions |
A synthetic androgen derived from ethinyl testosterone. Danazol indirectly reduces estrogen production by decreasing pituitary secretion of follicle-stimulating hormone and luteinizing hormone, and binds to sex hormone receptors in target tissues, thereby exhibiting antiestrogenic, anabolic and weakly androgenic effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C414" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C414" NCI Thesaurus) |
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ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039204 |
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altLabel |
Danocrine Bonzol 17alpha-ethynyl-17beta-hydroxy-4-androsteno[2,3-d]isoxazole Win-17757 DAN 1-ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental[7,8]phenanthro[3,2-d]isoxazol-1-ol Winobanin Danol Cyclomen (17alpha)-pregna-2,4-dien-20-yno[2,3-d]-isoxazol-17-ol Chronogyn Ladogal Danoval
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CAS Registry |
17230-88-5
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Component of | ||
cui |
C0733892 C0733889 C0813502 C0010961 C1511718 C1511717 C1527277
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Date last modified |
2006-12-12
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definition |
A synthetic androgen derived from ethinyl testosterone. Danazol indirectly reduces estrogen production by decreasing pituitary secretion of follicle-stimulating hormone and luteinizing hormone, and binds to sex hormone receptors in target tissues, thereby exhibiting antiestrogenic, anabolic and weakly androgenic effects. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C414" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C414" NCI Thesaurus)
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Legacy PDQ ID |
1827
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LT |
TRD
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NCI ID |
C414
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notation |
CDR0000039204
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NSC Code |
270916
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ORIG STY |
Drug/agent
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prefLabel |
danazol
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tui |
T125 T109 T121
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