Link to this page
Physician Data Query
| Preferred Name | diphenhydramine hydrochloride | |
| Synonyms |
Bendylate Benadryl Eldadryl SK-Diphenhydramine |
|
| Definitions |
The hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist with anti-allergic activity. Diphenhydramine hydrochloride competitively blocks H1receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries, and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C300" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C300" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039163 |
|
| altLabel |
Bendylate Benadryl Eldadryl SK-Diphenhydramine
|
|
| CAS Registry |
147-24-0
|
|
| cui |
C1527343 C0700902 C0004963 C0700899 C0700901
|
|
| definition |
The hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist with anti-allergic activity. Diphenhydramine hydrochloride competitively blocks H1receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries, and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C300" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C300" NCI Thesaurus)
|
|
| Legacy PDQ ID |
1783
|
|
| LT |
TRD
|
|
| NCI ID |
C300
|
|
| notation |
CDR0000039163
|
|
| NSC Code |
33299
|
|
| ORIG STY |
Drug/agent
|
|
| prefLabel |
diphenhydramine hydrochloride
|
|
| tui |
T109 T121
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |