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Physician Data Query
| Preferred Name | levamisole hydrochloride | |
| Synonyms |
Ergamisole Ketrax R 12564 Ergamisol ICI-59623 (-)-( S)-2,3,5, 6-tetrahydro-6-phenylimidazo [2,1-b] thiazole monohydrochloride RP-20605 Solaskil Ascaridil l-tetramisole hydrochloride LEV Decaris |
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| Definitions |
The orally bioavailable hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunostimulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiatiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C610" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C610" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039058 |
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| altLabel |
Ergamisole Ketrax R 12564 Ergamisol ICI-59623 (-)-( S)-2,3,5, 6-tetrahydro-6-phenylimidazo [2,1-b] thiazole monohydrochloride RP-20605 Solaskil Ascaridil l-tetramisole hydrochloride LEV Decaris
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| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000042385 http://purl.bioontology.org/ontology/PDQ/CDR0000039436 http://purl.bioontology.org/ontology/PDQ/CDR0000041452 http://purl.bioontology.org/ontology/PDQ/CDR0000041250 http://purl.bioontology.org/ontology/PDQ/CDR0000038857 http://purl.bioontology.org/ontology/PDQ/CDR0000039670 |
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| cui |
C1522430 C0720260 C0733387 C1517843 C0733384 C1522431 C1522429 C0733383 C0282217 C0023556 C0733385
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| Date last modified |
2010-06-04
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|
| definition |
The orally bioavailable hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunostimulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiatiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C610" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C610" NCI Thesaurus)
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| Legacy PDQ ID |
1642
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| LT |
TRD
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| NCI ID |
C610
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| notation |
CDR0000039058
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| ORIG STY |
Drug/agent
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| prefLabel |
levamisole hydrochloride
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| tui |
T109 T121
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