loading...| Preferred Name | rifabutin | |
| Synonyms |
Mycobutin |
|
| Definitions |
A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1408" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1408" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000037812 |
|
| altLabel |
Mycobutin |
|
| CAS Registry |
72559-06-9 |
|
| cui |
C0733659 C0140575 |
|
| definition |
A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1408" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1408" NCI Thesaurus) |
|
| Legacy PDQ ID |
1019 |
|
| LT |
TRD |
|
| NCI ID |
C1408 |
|
| notation |
CDR0000037812 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
rifabutin |
|
| tui |
T109 T195 |