Prostate Cancer Ontology

Last uploaded: June 6, 2023
Preferred Name

Triptorelin

Synonyms
Definitions

A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. (NCI04)/NCI-GLOSS Definition: A drug that is used to treat advanced prostate cancer, and is being studied in the treatment of breast cancer. It belongs to the family of hormonal drugs called gonadotropin-releasing hormone analogs.

ID

http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Triptorelin_castration

ChineseLabel

曲普瑞林

definition

A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. (NCI04)/NCI-GLOSS Definition: A drug that is used to treat advanced prostate cancer, and is being studied in the treatment of breast cancer. It belongs to the family of hormonal drugs called gonadotropin-releasing hormone analogs.

label

Triptorelin

prefixIRI

ProstateCancer:Triptorelin_castration

prefLabel

Triptorelin

reference

NCI Thesaurus Code:C1267

synonyms

TRIPTORELIN

6-D-Tryptophan-LH-RH

Triptorelin

Detryptoreline

triptorelin

6-D-Tryptophanluteinizing Hormone-releasing Factor

AY-25650

CL-118,532

Decapeptyl

URL

https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C1267

subClassOf

http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Medical_castration

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