loading...| Preferred Name |
Giant cell arteritis |
|
| Synonyms |
Horton disease |
|
| Definitions |
A rare large vessel vasculitis (LVV) characterized by vasculitis predominantly involving the arteries originating from the aortic arch and the extracranial branches of the carotid arteries. Clinical manifestations are variable, the predominant cranial phenotype is characterized by headache, jaw claudication, scalp tenderness and visual symptoms and the predominant LVV type by constitutional symptoms, polymyalgia rheumatica and occasionally limb ischemia. Overlaps between these two phenotypes are common. |
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| ID |
http://www.orpha.net/ORDO/Orphanet_397 |
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| alternative_term |
Horton disease Temporal arteritis |
|
| definition |
A rare large vessel vasculitis (LVV) characterized by vasculitis predominantly involving the arteries originating from the aortic arch and the extracranial branches of the carotid arteries. Clinical manifestations are variable, the predominant cranial phenotype is characterized by headache, jaw claudication, scalp tenderness and visual symptoms and the predominant LVV type by constitutional symptoms, polymyalgia rheumatica and occasionally limb ischemia. Overlaps between these two phenotypes are common. |
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| definition_citation |
Orphanet |
|
| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=397 |
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| has_age_of_onset |
Adult |
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| has_inheritance |
Multigenic/multifactorial |
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| hasDbXref |
MeSH:D013700 MedDRA:10018250 ICD-11:4A44.2 ICD-10:M31.6 OMIM:187360 UMLS:C0039483 |
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| label |
Giant cell arteritis |
|
| notation |
ORPHA:397 |
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| part_of | ||
| prefixIRI |
ORDO:Orphanet_397 |
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| prefLabel |
Giant cell arteritis |
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| present_in |
Germany AND has_point_prevalence_average_value : 8.9 AND has_point_prevalence_range : 1-9 / 100 000 Norway AND has_annual_incidence_average_value : 16.8 AND has_annual_incidence_range : 1-5 / 10 000 United Kingdom AND has_annual_incidence_average_value : 11.2 AND has_annual_incidence_range : 1-5 / 10 000 United States AND has_annual_incidence_average_value : 0.35 AND has_annual_incidence_range : 1-9 / 1 000 000 Italy AND has_point_prevalence_average_value : 30.4 AND has_point_prevalence_range : 1-5 / 10 000 Sweden AND has_annual_incidence_average_value : 7.7 AND has_annual_incidence_range : 1-9 / 100 000 Italy AND has_annual_incidence_average_value : 2.8 AND has_annual_incidence_range : 1-9 / 100 000 Europe AND has_point_prevalence_range : 1-5 / 10 000 |
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| treeView | ||
| subClassOf |