loading...| Preferred Name |
Plasmablastic lymphoma |
|
| Synonyms |
PBL |
|
| Definitions |
A rare aggressive B-cell non-Hodgkin lymphoma characterized by neoplastic cells resembling B immunoblasts or plasmablasts with a CD20-negative plasmacytic phenotype. The tumor may occur in the oral cavity, the gastrointestinal tract, or other, predominantly extranodal, sites and is typically associated with immunodeficiency or -suppression. The tumor cells are EBV-positive in most cases. Patients often present with disseminated bone involvement. Paraproteinemia may also be detected. Prognosis is generally poor. |
|
| ID |
http://www.orpha.net/ORDO/Orphanet_289666 |
|
| alternative_term |
PBL |
|
| definition |
A rare aggressive B-cell non-Hodgkin lymphoma characterized by neoplastic cells resembling B immunoblasts or plasmablasts with a CD20-negative plasmacytic phenotype. The tumor may occur in the oral cavity, the gastrointestinal tract, or other, predominantly extranodal, sites and is typically associated with immunodeficiency or -suppression. The tumor cells are EBV-positive in most cases. Patients often present with disseminated bone involvement. Paraproteinemia may also be detected. Prognosis is generally poor. |
|
| definition_citation |
Orphanet |
|
| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=en&Expert=289666 |
|
| hasDbXref |
ICD-10:C83.3 MedDRA:10065039 ICD-11:2A81.2 UMLS:C3472614 MeSH:D000069293 |
|
| label |
Plasmablastic lymphoma |
|
| notation |
ORPHA:289666 |
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| part_of | ||
| prefixIRI |
ORDO:Orphanet_289666 |
|
| prefLabel |
Plasmablastic lymphoma |
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| treeView | ||
| subClassOf |