loading...| Preferred Name | Calcineurin | |
| Synonyms |
Protein Phosphatase-2B PROTEIN PHOSPHATASE B 02 Protein Phosphatase 3 |
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| Definitions |
A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes. (source : MSH) |
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| ID |
http://doe-generated-ontology.com/OntoAD#C0054450 |
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| altLabel |
Protein Phosphatase-2B PROTEIN PHOSPHATASE B 02 Protein Phosphatase 3 |
|
| definition |
A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes. (source : MSH) |
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| gene_product_has_associated_anatomy | ||
| gene_product_plays_role_in_biological_process | ||
| hiddenLabel |
Calcineurin |
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| prefixIRI |
OntoAD:C0054450 |
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| prefLabel |
Calcineurin |
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| subClassOf |