Jump to:
loading...| Preferred Name | Didanosine [Chemical/Ingredient] | |
| Synonyms |
|
|
| ID |
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000006111 |
|
| code |
C22566 |
|
| Display_Name |
Didanosine |
|
| imported from | ||
| label |
Didanosine [Chemical/Ingredient] |
|
| MeSH_CUI |
M0024535 |
|
| MeSH_Definition |
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite. |
|
| MeSH_DUI |
D016049 |
|
| MeSH_Name |
Didanosine |
|
| NUI |
N0000006111 |
|
| prefixIRI |
NDF-RT:N0000006111 |
|
| prefLabel |
Didanosine [Chemical/Ingredient] |
|
| RxNorm_CUI |
3364 |
|
| RxNorm_Name |
Didanosine |
|
| Synonym |
2',3'-Dideoxyinosine ddI (Antiviral) Dideoxyinosine Inosine, 2',3'-dideoxy- |
|
| UMLS_CUI |
C0012133 |
|
| subClassOf |
Create mapping
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/NDFRT/N0000006111 | NDFRT | LOOM |