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Ontology of Drug Adverse Events
Last uploaded:
January 12, 2019
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| Id | http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000008043
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000008043
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|---|---|
| Preferred Name | Dideoxynucleosides [Chemical/Ingredient] |
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Dideoxynucleosides [Chemical/Ingredient]
|
|---|---|
| prefLabel |
Dideoxynucleosides [Chemical/Ingredient]
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| NUI |
N0000008043
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| Synonym |
ddNus
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| code |
C26450
|
| prefixIRI |
NDF-RT:N0000008043
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| RxNorm_CUI |
3365
|
| subClassOf | |
| imported from | |
| MeSH_CUI |
M0023387
|
| MeSH_DUI |
D015224
|
| type | |
| MeSH_Name |
Dideoxynucleosides
|
| UMLS_CUI |
C0012136
|
| Display_Name |
Dideoxynucleosides
|
| MeSH_Definition |
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
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