Ontology for Biomedical Investigations

Last uploaded: November 4, 2024
Preferred Name

binding assay
Synonyms
Definitions

An assay with the objective to characterize the disposition of two or more material entities to form a complex.

ID

http://purl.obolibrary.org/obo/OBI_0001146

Creator

Bjoern Peters

Jason Greenbaum

Randi Vita

editor preferred term

binding assay

example of usage

Determination of KD value for an antibody binding a protein using a BIACORE assay. Using plate bound antigen in an ELISA to determine if a mixture of serum antibodies bind the antigen. The following are NOT binding assays, as the desired output is not binding data: RNA microarray experiments to determine levels of gene expression. ChIP experiments to determine where in DNA a transcription factor binds. Using an IL-2 antibody on an ELISA plate to determine presence of IL-2 after stimulating a T cell culture.

has curation status

http://purl.obolibrary.org/obo/IAO_0000123

has participant

http://purl.obolibrary.org/obo/OBI_0001181

has_specified_output

http://purl.obolibrary.org/obo/OBI_0001181

label

binding assay

prefixIRI

OBI:0001146

prefLabel

binding assay

term editor

Bjoern Peters

Jason Greenbaum

Randi Vita

textual definition

An assay with the objective to characterize the disposition of two or more material entities to form a complex.

subClassOf

http://purl.obolibrary.org/obo/OBI_0000070

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