Preferred Name |
gefitinib |
|
Synonyms |
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Definitions |
A member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_49668 |
|
charge |
0 |
|
definition |
A member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer. |
|
formula |
C22H24ClFN4O3 |
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has characteristic | ||
has role | ||
inchi |
InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27) |
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inchikey |
XGALLCVXEZPNRQ-UHFFFAOYSA-N |
|
label |
gefitinib |
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mass |
446.910 |
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monoisotopicmass |
446.15210 |
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prefixIRI |
CHEBI:49668 |
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prefLabel |
gefitinib |
|
smiles |
C1=C(C(=CC=2C1=NC=NC2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4)OC |
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subClassOf |
http://purl.obolibrary.org/obo/CHEBI_35618 http://purl.obolibrary.org/obo/CHEBI_38530 http://purl.obolibrary.org/obo/CHEBI_50995 http://purl.obolibrary.org/obo/CHEBI_83403 http://purl.obolibrary.org/obo/CHEBI_38785 |