Preferred Name

loop of Henle
Synonyms

Henle's loop

ansa nephroni

Henle loop

Definitions

The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine.

ID

http://purl.obolibrary.org/obo/UBERON_0001288

alternative label

Henle's loop

ansa nephroni

Henle loop

continuous with

http://purl.obolibrary.org/obo/UBERON_0001292

http://purl.obolibrary.org/obo/UBERON_0001287

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0001231

database_cross_reference

Wikipedia:Loop_of_Henle

SCTID:361335009

VHOG:0001270

EMAPA:19280

UMLS:C0023986

MESH:D008138

BTO:0004608

NCIT:C33006

EV:0100390

FMA:17698

GAID:437

MA:0001675

definition

The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine.

depiction

http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png

dubious_for_taxon

http://purl.obolibrary.org/obo/NCBITaxon_8353

editor note

the definitions of some kidney parts (e.g. proximal straight tubule) refer to Henle's loop, even in species where this may not be present. Requires review.

external_definition

A highly specialized segment of the mammalian kidney tubules, that dips into the medulla. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, p.648, see_Liem_KF][VHOG]

function_notes

The loop of Henle plays an important role in creating a concentration gradient in the medulla of the kidney. It is involved in reabsorption of filtered water and ions including sodium, potassium and calcium, and independently regulates both the volume and osmolarity of body fluids.

has exact synonym

Henle's loop

ansa nephroni

Henle loop

has_obo_namespace

uberon

id

UBERON:0001288

in_subset

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

loop of Henle

notation

UBERON:0001288

note

The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine.

overlaps

http://purl.obolibrary.org/obo/UBERON_0001231

preferred label

loop of Henle

prefLabel

loop of Henle

present_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_8782

taxon_notes

The structure differs considerably between species; there is a definite physical loop of Henle in the mammalian and avian renal systems but this seems to be absent in Xenopus. However, homologs of some, but not all, molecular markers (e.g. cldn8 and clcnk) of the mammalian loop of Henle were found to be present in the pronephros of the frog larva .

subClassOf

http://purl.obolibrary.org/obo/UBERON_0007685

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Create mapping

Delete Mapping To Ontology Source
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