Preferred Name

pulmonary hemosiderosis
Synonyms

brown lung

brown induration

Idiopathic pulmonary hemosiderosis

Definitions

A lung disease with an unknown etiology affecting the lungs which results in bleeding from tiny alveolar capillaries. Examination of sputum and bronchoalveolar lavage fluid can disclose hemosiderin-laden alveolar macrophages (siderophages), and the lung biopsy shows numerous siderophages in the alveoli. Alveolar hemorrhage is characterized by hemoptysis, shortness of breath, alveolar infiltrates on chest radiograph, and various degrees of anaemia. Following a bleeding episode, the alveolar macrophages convert the hemoglobin's iron into hemosiderin within 36-72h.

ID

http://purl.obolibrary.org/obo/DOID_12118

alternative label

brown lung

brown induration

Idiopathic pulmonary hemosiderosis

database_cross_reference

SNOMEDCT_US_2023_03_01:190848001

OMIM:178550

OMIM:235500

UMLS_CUI:C0020807

ICD10CM:J84.03

MESH:C536281

ICD9CM:516.1

ORDO:99931

definition

A lung disease with an unknown etiology affecting the lungs which results in bleeding from tiny alveolar capillaries. Examination of sputum and bronchoalveolar lavage fluid can disclose hemosiderin-laden alveolar macrophages (siderophages), and the lung biopsy shows numerous siderophages in the alveoli. Alveolar hemorrhage is characterized by hemoptysis, shortness of breath, alveolar infiltrates on chest radiograph, and various degrees of anaemia. Following a bleeding episode, the alveolar macrophages convert the hemoglobin's iron into hemosiderin within 36-72h.

disease has location

http://purl.obolibrary.org/obo/UBERON_0002048

has exact synonym

brown lung

brown induration

Idiopathic pulmonary hemosiderosis

has symptom

http://purl.obolibrary.org/obo/SYMP_0000007

http://purl.obolibrary.org/obo/SYMP_0019153

has_alternative_id

DOID:0050330

has_obo_namespace

disease_ontology

id

DOID:12118

in_subset

http://purl.obolibrary.org/obo/doid#DO_rare_slim

label

pulmonary hemosiderosis

notation

DOID:12118

note

A lung disease with an unknown etiology affecting the lungs which results in bleeding from tiny alveolar capillaries. Examination of sputum and bronchoalveolar lavage fluid can disclose hemosiderin-laden alveolar macrophages (siderophages), and the lung biopsy shows numerous siderophages in the alveoli. Alveolar hemorrhage is characterized by hemoptysis, shortness of breath, alveolar infiltrates on chest radiograph, and various degrees of anaemia. Following a bleeding episode, the alveolar macrophages convert the hemoglobin's iron into hemosiderin within 36-72h.

preferred label

pulmonary hemosiderosis

prefLabel

pulmonary hemosiderosis

subClassOf

http://purl.obolibrary.org/obo/DOID_12119

http://purl.obolibrary.org/obo/DOID_850

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