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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Preferred Name | Transforming Growth Factor beta1 [Chemical/Ingredient] | |
| Synonyms |
TGF-beta1 TGF-beta-1 Transforming Growth Factor beta1 Transforming Growth Factor beta I |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000175326 |
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| altLabel |
TGF-beta1 TGF-beta-1 Transforming Growth Factor beta1 Transforming Growth Factor beta I
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|
| cui |
C1704256
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| MESH DEFINITION |
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
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| MESH DUI |
D053773
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| MeSH name |
Transforming Growth Factor beta1
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| MESH UI |
M0024760
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|
| NDFRT kind |
INGREDIENT_KIND
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|
| notation |
N0000175326
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|
| NUI |
N0000175326
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|
| prefLabel |
Transforming Growth Factor beta1 [Chemical/Ingredient]
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|
| tui |
T116 T123 T121
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| subClassOf |
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