loading...| Preferred Name | Transforming Growth Factor beta [Chemical/Ingredient] | |
| Synonyms |
TGF-beta Milk Growth Factor Bone-Derived Transforming Growth Factor Platelet Transforming Growth Factor Transforming Growth Factor beta TGFbeta |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170978 |
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| altLabel |
TGF-beta Milk Growth Factor Bone-Derived Transforming Growth Factor Platelet Transforming Growth Factor Transforming Growth Factor beta TGFbeta |
|
| cui |
C0040690 |
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| MESH DEFINITION |
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins. |
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| MESH DUI |
D016212 |
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| MeSH name |
Transforming Growth Factor beta |
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| MESH UI |
M0024757 |
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| NDFRT kind |
INGREDIENT_KIND |
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| notation |
N0000170978 |
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| NUI |
N0000170978 |
|
| prefLabel |
Transforming Growth Factor beta [Chemical/Ingredient] |
|
| tui |
T116 T123 |
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| subClassOf |