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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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Preferred Name | Transforming Growth Factor beta2 [Chemical/Ingredient] | |
Synonyms |
Polyergin Glioblastoma-Derived T-Cell Suppressor Factor TGF-beta2 TGF-beta-2 Transforming Growth Factor beta2 Suppressor Factor, T-Cell, Glioblastoma-Derived Cartilage-Inducing Factor-B BSC-1 Cell Growth Inhibitor |
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ID |
http://purl.bioontology.org/ontology/NDFRT/N0000175325 |
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altLabel |
Polyergin Glioblastoma-Derived T-Cell Suppressor Factor TGF-beta2 TGF-beta-2 Transforming Growth Factor beta2 Suppressor Factor, T-Cell, Glioblastoma-Derived Cartilage-Inducing Factor-B BSC-1 Cell Growth Inhibitor
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cui |
C0079441
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MESH DEFINITION |
A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
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MESH DUI |
D053781
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MeSH name |
Transforming Growth Factor beta2
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MESH UI |
M0024759
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NDFRT kind |
INGREDIENT_KIND
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notation |
N0000175325
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NUI |
N0000175325
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prefLabel |
Transforming Growth Factor beta2 [Chemical/Ingredient]
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tui |
T116 T123
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subClassOf |
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