Preferred Name

Transforming Growth Factor beta2 [Chemical/Ingredient]
Synonyms

Polyergin

Glioblastoma-Derived T-Cell Suppressor Factor

TGF-beta2

TGF-beta-2

Transforming Growth Factor beta2

Suppressor Factor, T-Cell, Glioblastoma-Derived

Cartilage-Inducing Factor-B

BSC-1 Cell Growth Inhibitor

ID

http://purl.bioontology.org/ontology/NDFRT/N0000175325

altLabel

Polyergin

Glioblastoma-Derived T-Cell Suppressor Factor

TGF-beta2

TGF-beta-2

Transforming Growth Factor beta2

Suppressor Factor, T-Cell, Glioblastoma-Derived

Cartilage-Inducing Factor-B

BSC-1 Cell Growth Inhibitor

cui

C0079441

MESH DEFINITION

A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.

MESH DUI

D053781

MeSH name

Transforming Growth Factor beta2

MESH UI

M0024759

NDFRT kind

INGREDIENT_KIND

notation

N0000175325

NUI

N0000175325

prefLabel

Transforming Growth Factor beta2 [Chemical/Ingredient]

tui

T116

T123

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000170978

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